TB vaccine Bharat Biotech begins clinical trials

Bharat Biotech International Ltd on Sunday said it started clinical trials of the Tuberculosis vaccine Mtbvac on adults in India. This is the first vaccine against Tuberculosis derived from a human source by the Spanish biopharmaceutical company, Biofabri, a press release from Bharat Biotech said.
The release said that Mtbvac is being developed for two purposes; firstly, as a more effective and potentially longer-lasting vaccine than BCG ( Bacillus Calmette Guerin) for newborns and secondly, for the prevention of TB in adults and adolescents, for whom there is currently no effective vaccine.
The trials are carried out by Bharat Biotech in close collaboration with Biofabri.
Trials to evaluate the safety and immunogenicity of Mtbvac have started with a pivotal safety, immunogenicity and efficacy trial which has been planned to start in 2025, the release said.
It is a giant step to test in adults and adolescents in the country where 28 per cent of the world’s TB cases accumulate. TB remains one of the world’s leading infectious causes of death, especially in India, Esteban Rodriguez, CEO of Biofabri said.